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This effect is achieved by the increased ROS formation (prooxidant effect), resulting in caspase 8 cleavage, inhibition of Janus kinase 2 (JAK2), and triggering regulator of apoptosis BAX, known as bcl-2-like protein 4

Without exercise, those extra protein calories might be stored as fat instead of supporting muscle maintenance

Extremely common

Studies reporting adjusted analyses had low to moderate risk of bias, whereas those reporting only crude estimates had a serious risk of bias, mainly due to confounding