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In APP/PS1 Alzheimer's mice, Dihexa treatment not only prevented cognitive decline but actively restored spatial learning abilities that had already been compromised, indicating the compound promotes recovery of function in damaged neural circuits

Overall, the role of arginine metabolism in pulmonary fibrosis is highly context-dependent, influenced by the interplay between the arginase and NOS pathways and the regulatory control of enzymes such as DDAH and ASS1

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Finally, the buffer was exchanged to PPS buffer using three serially connected 5 mL HiTrap Desalting Columns (GE Healthcare)