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Yes, topical glutathione is generally considered safe for daily use

Stummer et al

Werking en wetenschappelijke achtergrond Glutathione wordt in de literatuur beschreven als een centraal molecuul in de redox-huishouding van de cel en als cofactor in enzymatische ontgiftingsroutes, onder meer via glutathion-S-transferasen

For instance, reports indicate that patients using wellness peptides have no reliable information about whether they are safe or effective, according to warnings from ECRI and the Institute for Safe Medication Practices (ISMP)