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Article by Dr Christopher Leat Medical Director Envisage Clinic Benowa Dr Christopher Leat Medical Director Envisage Skin Clinic Founder and Director

Acknowledgements We thank E

Where appropriate, further investigation, such as testing glutathione status or DHFR genetic variants, may help explain why some individuals respond differently to folic acid and identify when alternative forms of folate may be beneficial

doi: 10.1186/s40168-015-0085-6 13 Norder GrusellEDahlnGRuthMNyLQuiding-JrbrinkMBergquistHet al