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Environmental Toxins : Exposure to pollution, chemicals, and heavy metals can reduce glutathione levels as the body works to detoxify harmful substances

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Our findings contribute to the paradigm that GSH usage by bacterial pathogens is complex and multifaceted, whereby certain pathogens rely on GSH as a nutrient source or protection from ROS, while others use it as a cue to sense the cytosol and initiate virulence, and some pathogens use GSH for multiple processes

The application of both drugs contributed to a considerable reduction in tumor volume in mice, decreasing from 100 mm3 to less than 3 mm3 after 21 days [139]