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A Brief History of GH Secretagogues The GH secretagogue story begins in the 1970s when Cyril Bowers discovered that small synthetic peptides based on enkephalin could release GH from pituitary cells without acting through opioid receptors

[DOI] [PMC free article] [PubMed] [Google Scholar] 2.Boyapati R.K., Dorward D.A., Tamborska A., Kalla R., Ventham N.T., Doherty M.K., Whitfield P.D., Gray M., Loane J., Rossi A.G., et al