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In response to LPS, the increase in GLP-1 is dose dependent, and GLP-1 levels remain elevated for 8-h (111)

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A separate Phase II study using 0.16 mg/kg subcutaneous injections across three 10-day cycles over 3 months reported significant melanin density increases by reflectance spectroscopy, with the largest gains in the fairest-skinned subjects (Barnetson et al., 2006)