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226 Quercetin also suppresses NF-B-mediated inflammatory responses, reducing pro-inflammatory cytokines (TNF-, IL-6, 227 induces autophagy to facilitate lipid droplet degradation, improving hepatic adaptation to metabolic stress

Journal of Investigative Medicine, 2022

While the expression pattern of the IGF system in animal models may not precisely mirror that in human AD, it is crucial to elucidate the pathophysiological role of the IGF system in AD through animal models and in vitro studies

Alexopoulos LG, Youn I, Bonaldo P, Guilak F