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Description

Lancet 397(10278):971984 Garvey WT, Frias JP, Jastreboff AM et al (2023) Tirzepatide once weekly for the treatment of obesity in people with type 2 diabetes (SURMOUNT-2): a double-blind, randomised, multicentre, placebo-controlled, phase 3 trial

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Neither should be overlooked

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Having depression is not necessarily a contraindication to GLP-1 treatment, but it requires careful consideration and monitoring

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However, this tightly regulated process can be disrupted, leading to persistent unresolved inflammation

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