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Analysis of the anti-psoriatic mechanism Existing studies have shown that OA may regulate keratinocyte differentiation through the retinoic acid receptor (RAR) pathway [46], and modulate abnormal proliferation of psoriatic keratinocytes by upregulating Notch1 expression to coordinate cellular autophagy [47]

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Am J Clin Nutr 2004

Activation of the antioxidant Nrf2 signaling by RTA-408 can effectively decrease the expression of lipid peroxidation-associated proteins, restore glucose metabolism and cytotoxicity of NK cells, and enhance their antitumor activity (101)