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The half-life of dulaglutide reached 90h , and the study showed that the hypoglycemic effect of its weekly injection was not inferior to that of daily injection of liraglutide

By improving insulin sensitivity and overall metabolic status, GLP1 receptor agonists can normalize reproductive hormone signaling in insulinresistant women (such as those with PCOS), which may help restore more regular ovulation

Steady-State Timeline and What to Expect During Dose Titration Most semaglutide dosing protocols follow a 4-week titration schedule aligned with pharmacokinetic accumulation

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