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Stability of GLP-1 analogs To evaluate the stability of GLP-1 and its analogs against DPP-IV activity, peptides were incubated at an initial concentration of 100 nM in DMEM containing 10% FBS or in 100% FBS at 37 for 0, 12, 24, 48, 72, and 96 hours in the presence or absence of 0.2 mM DPP-IV inhibitor diprotin A (Sigma-Aldrich, St Louis, MO, USA)