iih glp-1 The effect of agonist on idiopathic intracranial hypertension: a systematic review and meta-analysis Journal club: GLP-1 receptor agonists

Considering the diversity in body composition, diet, and health behaviours across populations, the authors note the importance of assessing how these drugs perform in different global contexts

8 L cells in the gastrointestinal tract sense the presence of nutrients in the gut lumen during feeding and secrete GLP-1 to act on multiple tissues, including the pancreas, intestines, and brain

12 The rapid acceptance of GLP-1 agonists, driven by their effectiveness against obesity, has gained substantial traction among medical professionals and patients, simultaneously igniting significant public and media interest

Sales of GLP-1 blockbusters soared from a modest EUR4.5bn in 2021 to a substantial EUR21.2bn in 2023