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Pate et al

Reyes-JimnezERamrez-HernndezASantos-lvarezJVelzquez-EnrquezJPina-CansecoSBaltirrez-HoyosRet alInvolvement of 4-Hydroxy-2-nonenal in the pathogenesis of pulmonary fibrosis

In addition, melatonin could increase catalase (antioxidant enzyme) activity to exert antioxidant effects, protect the sciatic nerve from vincristine-induced degeneration, and enhance the anticancer effect of vincristine

Nrf2 knockdown prevents NFT-dependent increase in cellular glutathione levels To examine the correlation between Nrf2 activation and the increase in glutathione levels after NFT treatment, Nrf2 protein levels were experimentally lowered by siRNA-mediated knockdown, which was confirmed by Western blotting (Fig