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As our data show, SnCE1 proteolytic processing occurs upon SIRT1-catalysed SnCE1 deacetylation, and AcK209 and AcK248 are not deacetylated by SIRT1, we conclude that Lys78, Lys94 and Lys98 in the N-terminal region are acetylation sites being involved in SnCE1 autoproteolytic processing

J Biol Chem 265:1291612926 Richards EM, Rosenthal RE, Kristian T, Fiskum G (2006) Postischemic hyperoxia reduces hippocampal pyruvate dehydrogenase activity

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