Copper is a powerful antioxidant which can fight against free radicals and slow down the effects of natural ageing
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The field needs validated, in vivocompatible flux sensors (O 2 , H 2 O 2 , NO/ONOO ) targeted to matrix/IMS, ER lumen, peroxisomes, plasma-membrane microdomains and nucleus, each with built-in specificity controls and reporting standards (matrix, oxygen tension, m, pH) to disambiguate signalling pulses from damage plateaus
It also plays a role in recycling other antioxidants, which is why its relationship with Vitamin C matters