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Care 22 (1), 188

- Efectos contextuales: parece funcionar mejor cuando hay alteracin de sueo por estrs, dolor o disrupcin neuroendocrina, ms que en todos los casos de insomnio

170 Smaller systematic reviews and metaanalyses based on fewer RCTs, reviews, and observational studies also reported that metformin reduced early pregnancy loss, 22 , 172 , 173 late miscarriage, 174 , 175 GDM, 22 , 170 , 172 , 173 , 176 preeclampsia, 22 , 173 PIH, 170 , 171 , 172 macrosomia, 170 and preterm delivery 170 , 172 , 173 , 174 , 177 , 178 in metforminexposed women with PCOS, with increased head circumference in offspring

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