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Rhein reverses Klotho repression via promoter demethylation and protects against kidney and bone injuries in mice with chronic kidney disease

doi: 10.1097/00000658-199010000-00005

Conversely, treatment regimens comprising Silver Nanoparticles, the general inhibitor L-NAME, the specific inhibitor, and a combination of cetirizine and histamine significantly attenuated iNOS mRNA transcription levels relative to the histamine-only treated group as shown in Figure 7