retatrutide and kidney function Diagram showing the mechanism of action of GLP-1 agonists in the treatment

Robert Kushner: Yeah, I call it the secret sauce

Endocrinology 141(3):12281235

In the diabetes TRIUMPH-2 trial, reported side effects included: Diarrhea (around 27 to 34 percent of participants, depending on the dose) Nausea (14 to 28 percent) Constipation (14 to 17 percent) Decreased appetite (6 to 17 percent) Vomiting (6 to 16 percent) In the TRIUMPH-3 trial for adults with severe obesity and heart disease, participants reported: Diarrhea (around 24 to 30 percent of participants, depending on the dose) Nausea (22 percent) Constipation (16 to 18 percent) Decreased appetite (14 to 15 percent) Hyperglycemia, or high blood sugar (3 to 4 percent) The high rates of diarrhea surprised Ali

Home / Before Your First Dose Prescribed, Not Started You've been prescribed GLP-1 but you haven't taken it yet