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Sections of rat synovial tissue were double incubated with anti-AR (1:250, Santa Cruz) and anti-Vimentin (1:250, Invitrogen) or anti-4-HNE-protein conjugate (1:250, Invitrogen) primary antibodies at 4 overnight

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Oral semaglutide was superior to placebo and other antihyperglycemic drugs, such as iDPP4 (sitagliptin), iSGLT2 (empagliflozin) or other arGLP-1 (liraglutide) in reducing HbA1c or weight.116 Oral semaglutide was well tolerated, with a safety profile similar to that of other arGLP-1 s