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Prognostic factors including MELD, KCH criteria and APACHE II scores have all been investigated as objective indicators to select liver transplantation candidates.51,52,62 Qualifying for liver transplantation not only requires a projected poor outcome and high risk of mortality based on these scoring systems but also necessitates a multidisciplinary approach that includes psychiatric evaluation, which may be challenging for patients who have intentionally overdosed on APAP

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Among 48 meta-analyses, 2 did not report primary studies