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Structural characterization is critical to ensure therapeutic integrity and efficacy
This study uncovers the significant role of peroxisomes-ether phospholipid axis in modulating susceptibility and evasion of iron dependent death, emphasizing that PUFA-ePLs represent a unique functional lipid category that is dynamically regulated during cellular state transitions, suggesting multiple regulatory nodes as potential therapeutic targets for diseases involving iron dependent death (Zou et al., 2020a)
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