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Pathophysiology can be classified in several ways, depending on the focus of study
The importance of being CG-rich and the curious case of Sox2 Transcription factors involved in adult neurogenesis are single-exon genes, for example, Sox2 , Sox4 , and Sox11 , or two-exon genes, for example, Ngn2 , NeuroD1, and NeuroD2 , that are embedded in long stretches of high CG densities (CpG islands)
Common approaches reduce weekly dose by 2030% (e.g., 0.5mg0.4mg0.3mg0.2mg0.1mgstop) or extend injection intervals before cessation