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Peppard PE, Young T, Palta M, Skatrud J

In addition to an assessment of semaglutide exposure levels, the aim of the present analysis was to provide additional details of the PK properties of semaglutide in terms of absorption, distribution and elimination and their relationships to covariate factors, in order to develop a novel disposition model that would be generally applicable across different routes of administration

FIGURE 13 4 Discussions Over the years following its discovery, GLP-1 has garnered significant attention for its incretin effect on glucoregulation in the management of T2DM, including its role in improving cardiovascular, respiratory, and renal functions (Singh et al., 2025b)