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Niacinamide (Vitamin B3): Brightens the complexion, evens skin tone, reduces the appearance of pores, and strengthens the skin barrier

Ecotoxicol Environ Saf 143:344350

Whilst we found that ex vivo vehicle treated cells produced high levels of cytokines, including IL-5, IL-13, IL-9 ( Supplementary Figures 4BD ), and modest amounts of IL-10 and IL-6 ( Supplementary Figures 4E, F ), melatonin treatment greatly reduced the concentration of all cytokines analyzed ( Supplementary Figures 4B F )

6 This suggests that glutathiones antioxidative properties can directly interfere with the viral life cycle, potentially reducing the severity and duration of cold sore outbreaks