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Pediatr Nephrol 20:313318 Schaefer F, Chen Y, Tsao T, Nouri P, Rabkin R (2001) Impaired JAK-STAT signal transduction contributes to growth hormone resistance in chronic uremia

These studies confirm that targeting IGFs is an important strategy for cancer therapy

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Researchers are also investigating whether these medications may lower cardiovascular risk by improving blood pressure, lipid levels, visceral fat, and inflammatory markers simultaneously