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Autophagy-targeting chimeras (AUTACs) selectively label damaged mitochondria for degradation through mechanisms distinct from the PINK1-Parkin pathway (Fig

Erythema that persists beyond 72 hours without improvement suggests delayed hypersensitivity or low-grade infection, both of which require clinical assessment before the next scheduled dose

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The recent identification of hybrid ketoacid dehydrogenase complexes between the E1 subunit of OADHc (DHTKD1) and the OGDHc 40 indicates that more complex crosstalk exists between ketoacid dehydrogenases, and we speculate that these hybrid complexes may be more susceptible to acyl-lipoyl adduct formation