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Niacinamide and 2-MNG Combination: A topical regimen combining niacinamide (10%) and 2-mercaptonicotinoyl glycine (2-MNG, 0.5%) showed significant clinical efficacy in reducing facial dyschromia and post-inflammatory hyperpigmentation across diverse skin phototypes [209,210,211,212]

Corticosteroids (prednisolone or dexamethasone and others) Thyroid medications (levothyroxin) Insulin and sulfonylurea Oral estrogens Somatostatin analogs or the drugs that affect somatostatin (Levodopa) Clonidine and certain beta blockers Tell your doctor about all the medications you are taking before starting the Sermorelin therapy

doi: 10.1021/cb400380s 105 LewinARReidLEMcMahonMStarkGRKerrIM

However, in a later study, it has been demonstrated that direct phosphorylation of NRF2 by MAPKs has a limited contribution in modulating NRF2 activity