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Progression to kidney replacement therapy (KRT) occurred in 3.7% of patients receiving GLP-1 receptor agonists

Proper titration following the recommended schedule is the most important factor in minimizing side effects with either compound

Maintain the same total daily dose of sitagliptin and metformin when changing between JANUMET (sitagliptin and metformin HCl immediate-release) and JANUMET XR

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