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Rather than focusing only on whether a side effect occurs, providers also evaluate treatment response, symptom changes, medical history, laboratory findings when appropriate, and overall health throughout therapy

Patients switching due to plateau on one medication often experience renewed weight loss on the other

Clinical Trials in Pediatric Patients Aged 10 to 17 Years with Type 2 Diabetes Mellitus Dapagliflozin The dapagliflozin safety profile observed in the 26-week placebo-controlled clinical trial with a 26-week extension in 157 pediatric patients aged 10 years and older with type 2 diabetes mellitus was similar to that observed in adults [see Clinical Studies (14.2)]

Its important to highlight that peptides like GLP-1 RAs are now being integrated into broader therapeutic strategies, such as fixed-dose combinations with insulin, dual or triple agonists