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It progresses gradually due to a combination of genetic predisposition and hormonal changes, particularly the effects of dihydrotestosterone (DHT) on hair follicles

A cornerstone of the new act is the creation of Strategic Breakthrough awards, which allow for Phase II funding of up to $30 million for critical technologies, provided there are 100% matching funds

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In recent years, as a result of advances in the understanding of the pathogenesis of type 2 diabetes, new drugs with novel mechanisms of action and different safety profiles have been developed, including compounds with incretin effect and glucosuric drugs acting in disorders at intestinal and renal level present in DM2