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doi: 10.1093/brain/awy132 32 HeL.YangW.YangP.ZhangX.ZhangA

Safety and efficacy of a new micronized formulation of the ALIAmide palmitoylglucosamine in preclinical models of inflammation and osteoarthritis pain

The median gene effect score for HMGCR across the 1,078 cell lines contained in DepMap was 1.14, and the gene effect score for all but 1 cell line was below 0 (Figure 1A, Table S1)

Esters of sterols have a higher activity and better fat solubility, which allows for lower effective dosages (23 grams/day as opposed to 510 grams/day for unesterified sterols)