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Selective Targeting of TP53-Y220C Mutant AML By PC14586 Results in TP53 Wild-Type Conformation and Synergistical Apoptosis Induction By Concomitant Inhibition of Xpo-1, MDM2, or Bcl-2

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BPC-157 has shown angiogenic and vasculo-protective effects in rodents, with proposed involvement of the nitric-oxide and VEGFR2 pathways