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Description

Disease burden and epidemiological trends of chronic kidney disease at the global, regional, national levels from 1990 to 2019

The typical dosing schedule begins with 0.25 mg once weekly for 4 weeks (as an initial dose for tolerability adjustment), then increases to 0.5 mg once weekly

Although this approach to handling of intercurrent events may be reflective of clinical practice, it can be a limitation for the interpretation of efficacy results given that these intercurrent events also have an effect on CV risk

It will have a beyond-use date of approximately one month after the patient receives it