DrWS: Yeah, so when youre going after big disease processes, when youre really starting to try to make a difference in Crohns or inflammatory bowel, things that are hot and not great, youre looking to hit them with everything youve got
The mechanism leading to 5-oxoprolinuria is the following: decreased activity of 5-oxoprolinase leads to decreased conversion of 5-oxoproline to glutamate
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Medications that interfere include certain antidepressants (SSRIs, SNRIs), beta blockers, steroids, and antipsychotics