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The potential mechanisms underlying the increased risk of gastric aspiration are not fully understood, and nowadays it is explained mainly by delayed gastric emptying and inhibition of gastrointestinal motor function that GLP-1-RAs exert through both central motor nuclei and vagal afferents [13, 14]

However, the data on this is not yet conclusive

Even the lowest maintenance dose of 5 mg produced meaningful results, averaging around 15% body weight reduction

avoid eating close to bedtime Ginger and bland foods : Some patients find ginger tea or bland foods (toast, crackers, rice) helpful during episodes of nausea Slow eating : Chew food thoroughly and eat slowly to reduce gastric distress If nausea is severe or persistent, contact your GP or diabetes specialist nurse