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In a groundbreaking investigation, Frejlachova et al
Among the tissues and organs crucial in regulating glucose and lipid metabolism, pancreas, brain, and adipocytes express GIP receptors (GIPRs), while pancreas, brain, and gastrointestinal tract are rich in GLP-1 receptors (GLP-1Rs) (40)
Their core value lies in synergizing with conventional treatments to enhance efficacy and reduce adverse effects, addressing unmet needs in ADs such as long-term remission maintenance and slowing early disease progression, without replacing core first-line therapies
doi: 10.1038/s41398-020-01039-2 76 SykesDLHoldsworthLJawadNGunasekeraPMoriceAHCrooksMG
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