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It is characterized by ROS-induced dissociation of the oxygen-sensitive kinase KEAP1, activating the NRF2 signaling pathway and caspase-8-dependent cell death [241, 242]

Data presentation details: To view or add a comment, sign in An NHS-approved drug could be repurposed to prevent breast cancer in pre-menopausal women with a strong family history of the disease, researchers have found