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Currently, there are other dual GIPR/GLP-1R agonists available, such as GLP-1R/GR (glucagon receptor), GLP-1R/AR (amylin receptor), and GLP-1R/NPYR (peptide YY binds to neuropeptide Y receptors) [36, 115] and even triple agonists that can activate GIPR to treat obesity and T2DM
Possible Side Effects Like other incretin-based therapies, Retatrutide may cause some side effects
Users consistently describe being able to see food, feel hungry at a low background level, but have zero compulsion to overeat
Most of my patients are on it for the diagnosis of diabetes as well, so I dont have much experience with discontinuation
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