1 These include imipramine (Tofranil), midodrine (ProAmatine), chlorpheniramine (Chlor-Trimeton), brompheniramine (Veltane), ephedrine (Akovaz), pseudoephedrine (Sudafed), and phenylephrine (Vazculep)
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The lowest quartile of patients had GGT values between 1 U/L and 11 U/L in men and 1 U/L and 6 U/L in women, and the highest quartile included men with GGT values from 25 U/L to 99 U/L and women with GGT values from 14 U/L to 88 U/L
[3] [5] While the different mechanisms for desensitization are still being characterized, there are currently four known mechanisms: uncoupling of receptors from associated G proteins, endocytosis, degradation, and downregulation