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This dosage can be increased to 1.5 mg once weekly if necessary

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For patients with skin-brightening goals or specific pigmentation concerns, a range of evidence-supported topical and procedural treatments are available

91 : 743745 Stahnke K, Fulda S, Friesen C, Strauss G and Debatin K-M (2001) Activation of apoptosis pathways in peripheral blood lymphocytes by in vivo chemotherapy