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By supplementing with the fumarate form of L-carnitine, you are simultaneously providing the transport vehicle for fatty acids and a direct, readily usable substrate to fuel the Krebs cycle

Bradley EH, Sipsma H, Taylor LA

Clinical trials have demonstrated that adding a GLP1-RA to patients already receiving SGLT2is is cardiovascularly safe [65] and may even reduce cardiovascular events [19]

This isn't deterministicit provides context for personalized strategy selection