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Activation of genes encoding antioxidant enzymes such as catalases and GST1 was detected in the tissue surrounding the initial infection site (Schenk et al., 2000)

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However, they did observe improvements in overall cardiometabolic health and cardiovascular disease risk, including a significant decline in C-reactive protein (an inflammation biomarker), a significant decrease in 10-year cardiovascular disease risk scores and trend toward improved oxygen consumption