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To model biotinylated cysteine, a residue was initially parameterized with the General Amber Force Field (GAFF) via OpenMMs residue template generator, then modified to incorporate partial charges from the disulfide-bonded cysteine CYX residue and protein parameters from Amber ff14SB 44

individuals with a history of certain endocrine cancers, pancreatitis or severe gastrointestinal disease

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Obesity can cause a number of complications, such as Type 2 diabetes, high cholesterol, metabolic syndrome, high blood pressure, heart attack, stroke, and sleep apnea