Positioned strategically throughout the central nervous system (CNS), in the meninges, choroid plexus, perivascular spaces, and even adjacent to neurons, mast cells maintain close contact with neurons, glia, and endothelial cells
NT: Conceptualization, Project administration, Supervision, Writingoriginal draft, Writingreview and editing
Working as expected with little side effects
Two articles from the 1990s, recounting in vitro experiments, showed that NT was a potent constrictor of airway muscles [23,24], while a later study showed the opposite effect in the form of NT-mediated inhibition of guinea pig cholinergic and noncholinergic bronchial ring contraction evoked by electrical field stimulation [25]