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Enteric Nervous System Modulation BPC-157 directly increased survival of cultured enteric neurons under stress conditions and enhanced proliferation of enteric glial cells (which support neuronal function and participate in gut immune homeostasis)

That single human study was a 12-patient retrospective case series of intra-articular BPC-157 injection for chronic knee pain, in which 7 of 12 patients (58%) reported self-described relief lasting more than 6 months

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