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Advanced disease models, including genetically stratified organoids, patient-derived iPSC lines, and age-appropriate 3D brain cultures, may offer more refined platforms to dissect these differences and identify compound-subtype associations (Sirkis et al., 2022)

J Neurol 254(12):16761683 Kumar P, Kalonia H, Kumar A (2010) Nitric oxide mechanism in the protective effect of antidepressants against 3-nitropropionic acid-induced cognitive deficit, glutathione and mitochondrial alterations in animal model of Huntingtons disease

Dihexa, a synthetic mimetic of Angiotensin IV, is a peptide of particular interest in neuroscience, studied for its potent neurogenic and synaptogenic capabilities

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