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[DOI] [PubMed] [Google Scholar] 186.Heffernan M, Summers RJ, Thorburn A, Ogru E, Gianello R, Jiang WJ, Ng FM

Methylcobalamin, a form of B12, is particularly essential for synthesizing neuronal lipids, regenerating axonal nerves, and exerting neuroprotective effects, potentially improving conditions such as Alzheimer's disease, Parkinsonism, and dementia, while also serving as an approved treatment for peripheral neuropathy

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Individual response times vary considerably, but most people notice initial effects within 2-4 weeks of consistent supplementation