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10,11 Curcumin Preclinical and in vitro data suggest that curcumin can inhibit DPP-4 activity and enhance glycemic control in diabetic animal models, potentially prolonging the active life of GLP-1, although this has not been confirmed in human mechanistic studies

Our approach combines nutritional counseling, behavioral modification techniques, physical activity recommendations, and FDA-approved prescription medications when appropriate

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Results from Eli Lilly's Phase 2 trial (Jastreboff et al., New England Journal of Medicine, 2023) reported mean body weight reductions of approximately 1724% over 48 weeks depending on dose, which has generated considerable scientific interest