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In the efficacy-estimand analysis, participants taking the highest dose (12 mg) lost an average of 28.7% of their body weight at 68 weeks, about 71.2 pounds from a baseline of 248.5 pounds

The broader context though shows that supply issues have been fairly consistent for some months now compared to record highs two years ago

Malignant mesothelioma mortality United States, 1999-2015

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